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A blend of polyphenolic compounds explains the stimulatory effect of red wine on human endothelial NO synthase

✍ Scribed by Thomas Wallerath; Huige Li; Ute Gödtel-Ambrust; Petra M. Schwarz; Ulrich Förstermann

Book ID
116789928
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
574 KB
Volume
12
Category
Article
ISSN
1089-8603

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The red wine extract-induced activation of endothelial nitric oxide synthase is mediated by a great variety of polyphenolic compounds
✍ Cyril Auger; Mehdi Chaabi; Eric Anselm; Annelise Lobstein; Valérie B. Schini-Ker 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 471 KB

## Abstract Phenolic extracts from red wine (RWPs) have been shown to induce nitric oxide (NO)‐mediated vasoprotective effects, mainly by causing the PI3‐kinase/Akt‐dependent activation of endothelial NO synthase (eNOS). RWPs contain several hundreds of phenolic compounds. The aim of the present st