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A bispecific antibody detects cytotoxic T lymphocytes of unknown antigen specificity in patients with granular lymphocyte-proliferative disorders

โœ Scribed by Dr Takako Kaneko; Kazuo Oshimi; Takashi Seto; Ko Okumura; Hideaki Mizoguchi


Book ID
114713054
Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
494 KB
Volume
80
Category
Article
ISSN
0007-1048

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Of 27 patients with granular lymphocyte-proliferative disorders (GLPD), 18 patients had CD3' T-cell-lineage GLPD (T-GLPD), and 9 patients had CD3-CD16' natural killer (NK) cell-lineage GLPD (NK-GLPD). In 9 of the 18 patients with T-GLPD, severe anemia of ~7 . 5 g/dl hemoglobin (mean 5.4 g/dl) and er