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A bimolecular mechanism for the cell size control of the cell cycle

✍ Scribed by L. Alberghina; E. Martegani; L. Mariani; G. Bortolan


Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
652 KB
Volume
16
Category
Article
ISSN
0303-2647

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## Abstract The serine/threonine kinase PAK4 regulates cytoskeletal architecture, and controls cell proliferation and survival. In most adult tissues PAK4 is expressed at low levels, but overexpression of PAK4 is associated with uncontrolled proliferation, inappropriate cell survival, and oncogenic