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A biliary milestone: Functional expression of the human bile salt export pump

✍ Scribed by James L. Boyer

Book ID
119756820
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
65 KB
Volume
123
Category
Article
ISSN
0016-5085

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Cloning of the dog bile salt export pump
Cloning of the dog bile salt export pump (BSEP; ABCB11) and functional comparison with the human and rat proteins
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## Abstract The dog bile salt export pump (BSEP; ABCB11) was cloned and expressed in a Sf9 insect cell system. The deduced amino acid sequence encodes a 1325‐amino‐acid protein, which shows 89.4% and 80.2% homology with human BSEP and rat Bsep, respectively. The transcript of the dog Bsep gene was