A significant portion of published literature is dedicated to describing the cloning and the characterization of proteins involved in the progression of the cell cycle, which govern cell growth both in cancer and normal ontogenesis. With this abundance of information, the cascading pathways of molec
โฆ LIBER โฆ
A better cell cycle target for gene therapy of colorectal cancer: Cyclin G
โ Scribed by Rodrigo Perez; Nancy Wu; Adam A. Klipfel; Robert W. Beart
- Book ID
- 107408943
- Publisher
- Springer-Verlag
- Year
- 2003
- Tongue
- English
- Weight
- 233 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1091-255X
No coin nor oath required. For personal study only.
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## Abstract This study focused on a cell cycle regulatory gene, __FBXW7__, which ubiquitinates cโMyc and cyclin E and promotes exit from the cell cycle. We determined the expression level of __FBXW7__ in colorectal cancer (CRC) cases, correlated those values with clinicopathologic features, and cha
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