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A bayesian nonparametric approach to determining a maximum tolerated dose

✍ Scribed by Pietro Muliere; Stephen Walker


Book ID
104340321
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
739 KB
Volume
61
Category
Article
ISSN
0378-3758

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✦ Synopsis


This paper presents a Bayesian nonparametric approach to determining a maximum tolerated dose. Typically, this would be carried out in a phase I trial. We describe a design and analysis which makes use of the Polya tree prior distributions.


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