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A base-controlled regioselective synthesis of allyl and vinyl phenyl sulfones

✍ Scribed by Dana, Dibyendu; Davalos, Anibal R.; Subramaniam, Gopal; Afzal, Nisar; Hersh, William H.; Kumar, Sanjai


Book ID
120189817
Publisher
Elsevier Science
Year
2013
Tongue
French
Weight
587 KB
Volume
54
Category
Article
ISSN
0040-4039

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The synthesis of y-functionalized vinyl sulfonea 3 have been carried out directly starting from dibromldes 2 derived from ally1 sulfones 1 by reaction with different nucleophiles. The process is stereoselective affording compounds 3 with E configuration except in the case of methallylic derivatives.