WHEREAS it is universally accepted that bacterial infection is the probable cause of niost cases of cholelithiasis, it is by no means certain that the particular bacteria iisiially cited as the causal agents are of necessity-the primary pathogenic organisms, nor has the route of priniary infection been definitely established : blood-stream, lymphatics, and bile-passages have all been regarded a s t,he possible channel by which the bacteria have reached the gall-bladder. Tlibk I . -B A C T E R I h ISOLATED FROM GALL-BLADDER WALL, F R O M BILE, AND FROM STOXIIS. ('ASES .iK.4LYSIS All thrw tissues infected 1 3 Wall and bile only . . 3 1 Slr. frc.crtli.9 ; 1 S l a . albus ; 1 B. zeelchii FVaIl only Stonc only . . * . 1 1 B. zaPlchii All three tissues sterile I) (i B. coli ; 3 S l r .
freculis ; 2 Sin. albus ; 2 B. welchii 3 B. coli ; 1 H. pnralyphosiis β¬3 ; 7 Sir. fa?calis ; 3 Sta. itlbus; 1 Slri. aitrcus ; * 8 11. zcelchii ; t 7 mixed. .. . . 2.3 * Oiw c'ilsr, i i o sttin-' 11iii<I ' riiil) t Mircil iiifrctioii : 2 ti. c d i + A . i r d u k i i . 2 It. mli + Slr. 50 Jwmlia 2 B . c d i + Sfu. ulbrrr. 1 H. ucirli laeiiri + Sfr. -/wnrlis -* This patient had also exhibited achylia.