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A 7–34 analog of the parathyroid hormone-related protein has potent antagonist and partial agonist activity in vivo

✍ Scribed by Horiuchi, Noboru; Hongo, Takashi; Clemens, Thomas L.


Book ID
123204252
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
535 KB
Volume
12
Category
Article
ISSN
0169-6009

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Evaluation in vivo of a potent parathyro
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In an effort to design and select potent parathyroid hormone (PTH) antagonists suitable for clinical utility, a PTH analog was evaluated in vivo in an animal model to assess its properties in preparation for human studies. The previously described PTH antagonist, [Nles. '8,Ty84] bPTH(7-34)NH2, which