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A 30-kDa fragment of insulin-like growth factor (IGF) binding protein-3 in human pregnancy serum with strongly reduced IGF-I binding

✍ Scribed by M. Ahlsén; C. Carlsson-Skwirut; A. P. Jonsson; E. Cederlund; T. Bergman; P. Bang


Book ID
105758659
Publisher
Springer
Year
2007
Tongue
English
Weight
528 KB
Volume
64
Category
Article
ISSN
1420-682X

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Insulin-like growth factor (IGF) binding
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## Abstract While extracellular acidification within solid tumors is well‐documented, how reduced pH impacts regulation of insulin‐like growth factor‐I (IGF‐I) has not been studied extensively. Because IGF‐I receptor binding is affected by IGF binding proteins (IGFBPs), we examined how pH impacted