Cyclopropanation of nitroso Diels–Alder
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Cheng Ji; Marvin J. Miller
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Article
📅
2010
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Elsevier Science
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French
⚖ 999 KB
Treatment of nitroso Diels-Alder cycloadducts 1 with diazomethane in the presence of palladium acetate gives synthetically useful exo-6-oxa-7-azatricyclo[3.2.1.02,4]octane derivatives 7 in good to excellent yield. Using this methodology, a conformationally restricted 2',3'-methano carbocyclic nucleo