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A 1H-NMR study of the solution conformation of cyclo(GRGDSPA): Conformational effects on the physiological activity

✍ Scribed by Ryuta Mizutani; Ichio Shimada; Yukio Ueno; Masafumi Yoda; Hiromichi Kumagai; Yoji Arata

Book ID
115765609
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
437 KB
Volume
182
Category
Article
ISSN
0006-291X

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## Abstract The ^1^H‐ and ^13^C‐NMR. spectra of cyclo‐tetraglycyl show that the four peptide groups are magnetically equivalent, and different from either a standard __trans__ or a standard __cis__ peptide group. It is suggested that the observed NMR. features correspond to a non‐planar form of the