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A 15N NMR study of intermolecular interactions between vancomycin and Ac-d-Ala-d-Ala

✍ Scribed by Geoffrey E Hawkes; Henriette Molinari; Surinder Singh; Lu-Yun Lian


Book ID
103191702
Publisher
Elsevier Science
Year
1987
Weight
272 KB
Volume
74
Category
Article
ISSN
0022-2364

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H and 13C NMR spectra of AC-PSer-Gly, Ala-PSer-Gly and Gly-PSer-Phe have been measured and analysed as a function of pD. The NMR parameters of the Beryl side chain are a function of the sequence. The second titration step of the phosphate group (pK, = 5.7) is much more difEcdt to detect in AcPSer-Gl