A 1:1 co-crystal of quinol and pyridine

✍ Scribed by Oswald, Iain D. H. ;Motherwell, W. D. Sam ;Parsons, Simon

• Book ID: 104482687
• Publisher: International Union of Crystallography
• Year: 2004
• Tongue: English
• Weight: 376 KB
• Volume: 60
• Category: Article
• ISSN: 1600-5368
• DOI: 10.1107/s1600536804024547

✦ Synopsis

A co-crystal of quinol and pyridine would be expected to form with 1:2 stoichiometry because quinol has two hydrogen-bond donors and pyridine has one hydrogen-bond acceptor which is more basic than phenolic oxygen. We report the structure of a 1:1 co-crystal, viz. quinol±pyridine (1/1), C 6 H 6 O 2 ÁC 5 H 5 N, which does not conform to this expectation. Its stability appears to imply that a combination of individually relatively weak CÐHÁ Á ÁO, CÐHÁ Á Á% and %±% stacking interactions are energetically competitive with OÐHÁ Á ÁN hydrogen bonds. Quinol molecules lie on inversion centres, while pyridine is in a general position.