𝔖 Bobbio Scriptorium
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99mTc−Sn oxine complex: A radiocompound with possibilities for lymphographic studies

✍ Scribed by L. J. Anghileri; N. Firusian; M. Heidbereder

Book ID
104684175
Publisher
Springer
Year
1977
Tongue
English
Weight
196 KB
Volume
2
Category
Article
ISSN
0340-6997

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✦ Synopsis

A very simple method of preparation of 99mTc-Sn oxine which shows a high yield of radioactive labeling is described in this paper. After intravenous injection the radiocolloid is taken up mainly by the reticuloendothelium. The subcutaneous administration indicates a good migration through the tissues and a high accumulation by lymph nodes, characteristics which point to the usefulness of this radiocompound for lymphographic studies.

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A new 99mTc-phosphine-isocyanide complex with the general structure [99mTc (DEPE)2(CNR)2]+ has been synthesised and tested in animals and one human. In three animal species (rat, rabbit, dog), the complex is an efficient myocardial imaging agent, while in humans it remains in the blood pool. The com