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98 Molecular and clinical study of two patients with homozygous familial hypercholesterolemia


Book ID
117638725
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
157 KB
Volume
15
Category
Article
ISSN
0939-4753

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Homozygous familial hypercholesterolemia
โœ Roy Beigel; Yitzhak Beigel ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 97 KB

## Abstract Familial hypercholesterolemia (FH) is an autosomal dominant disease. Homozygous FH (HFH) manifests with severe hypercholesterolemia since birth (cholesterol levels >5โ€“6 the upper normal limit), which, if untreated, leads to early onset accelerated atherosclerosis and premature coronary