963-18 Reoxygenation Following Hypoxia Induces the Reorganization of the Actin Cytoskeleton of Endothelial Cells
β Scribed by Lawrence E. Crawford; Jay L. Zweier; Pascal J. Goldschmidt-Clermont
- Book ID
- 119172002
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 141 KB
- Volume
- 25
- Category
- Article
- ISSN
- 1558-3597
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## Abstract In previous works we showed that the depolarization of the plasma membrane potential (PMP) determines a reorganization of the cytoskeleton of diverse epithelia in culture, consisting mainly of a reallocation of peripheral actin toward the cell center, ultimately provoking intercellular
Vascular endothelial cells (EC), communicating with one another across gap junctions, are usually made dysfunctional by hypoxia and reoxygenation (H/R); however, very limited information exists regarding the effects of H/R on the endothelial gap junctions. We investigated whether H/R interferes with