Chromatographic analysis and pharmacokin
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Leanne Embree; Karen A. Gelmon; Andreas Lohr; Lawrence D. Mayer; Andrew J. Coldm
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Article
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1993
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John Wiley and Sons
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English
⚖ 1024 KB
A sensitive and specific quantitative assay for total doxorubicin concentrations in plasma containing liposome-encapsulated doxorubicin hydrochloride (TLC D-99) was developed, with solvent extraction and reversed-phase high-performance liquid chromatography (HPLC). Separation of doxorubicin from its