94368665 Effects of hormone replacement therapy on reactivity of atherosclerotic coronary arteries in cynomolgus monkeys
β Scribed by J. Koudy Williams; E.K. Honore; S.A. Washburn; T.B. Clarkson
- Book ID
- 116135684
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 108 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0378-5122
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## Abstract ## Objective To determine the effects of longβterm estrogen replacement therapy (ERT) on the severity of osteoarthritis (OA) of the knee joint in surgically postmenopausal (bilaterally ovariectomized) female monkeys. A secondary aim was to evaluate the effect of soy phytoestrogen (SPE)
The aim of this study was to determine cytosolic estrogen receptor content of the cynomolgus monkey bladder and vagina after hormone replacement therapy. Animals maintained without hormone therapy for 2 years after surgical menopause were randomized to receive either no hormones (OVX), conjugated eq