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9411 The novel HSP90 inhibitor NVP-AUY922 demonstrates activity in rhabdomyosarcoma cell lines

✍ Scribed by Slater, O.; Renshaw, J.; Workman, P.; Pritchard-Jones, K.


Book ID
123085033
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
44 KB
Volume
7
Category
Article
ISSN
1359-6349

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## Abstract Osteosarcoma (OSA), the most common malignant bone tumor in dogs and children, exhibits a similar clinical presentation and molecular biology in both species. Unfortunately, 30–40% of children and 90% of dogs still die of disease despite aggressive therapy. The purpose of this study was