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937 Inhibitors of Bcl-3 as a Novel Therapeutic Strategy for HER2+ Breast Cancer

✍ Scribed by J. Soukupova; A. Brancale; A. Westwell; R. Clarkson

Book ID: 117663390
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 58 KB
Volume: 48
Category: Article
ISSN: 0959-8049
DOI: 10.1016/s0959-8049(12)71558-7

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## Abstract We designed our experiments to evaluate whether fatty acid synthase (FAS), a lipogenic enzyme linked to tumor virulence in population studies of human cancer, is necessary for the malignant transformation induced by Her‐2/neu (erbB‐2) oncogene, which is overexpressed not only in invasiv