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934 POSTER Phase II study of irinotecan and oral etoposide in patients with platinum/taxane-resistant ovarian carcinoma


Book ID
118623510
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
144 KB
Volume
3
Category
Article
ISSN
1359-6349

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Sequential topotecan and oral etoposide
✍ Bo Gronlund; Svend A. Engelholm; GyΓΆrgy Horvath; Johanna MΓ€enpÀÀ; Mona Ridderhei πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 100 KB πŸ‘ 1 views

## Abstract ## BACKGROUND The objectives of this study were to determine the maximum tolerable dose (MTD), toxicity, efficacy, and feasibility of a sequential regimen of fixed‐dose topotecan (1.00 mg/m^2^ on Days 1–5) and increasing doses of oral etoposide (50 mg, 75 mg, and 100 mg on Days 6–12 or