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932 Long-term productive replication of hepatitis B virus (HBV) in the liver by single intravenous injection of naked HBV DNA in immunocompromised mice

✍ Scribed by Takahiro Suzuki; Tetsuo Takehara; Kazuyoshi Ohkawa; Hisashi Ishida; Chihiro Ohnishi; Masahisa Jinushi; Takuya Miyagi; Norio Hayashi


Book ID
119530834
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
128 KB
Volume
38
Category
Article
ISSN
0270-9139

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✍ Nelson Ruiz-Opazo; Prasanta R. Chakraborty; David A. Shafritz πŸ“‚ Article πŸ“… 1982 πŸ› John Wiley and Sons 🌐 English βš– 787 KB

## Abstract In chimpanzee hepatitis B virus (HBV) carriers, the molecular mechanism for viral persistence has been examined by analyzing the properties of viral DNA molecules in liver and serum. Two extrachromosomal HBV‐DNA molecules migrating on Southern blots at 4.0 kb and 2.3 kb were observed in