Increased sensitivity of KRAS mutation d
✍
Lasse S. Kristensen; Iben L. Daugaard; Mariann Christensen; Stephen Hamilton-Dut
📂
Article
📅
2010
🏛
John Wiley and Sons
🌐
English
⚖ 417 KB
Considerable effort has been invested in the development of sophisticated technologies enabling detection of clinically significant low-level tumor specific KRAS mutations. Coamplification at lower denaturation temperature-PCR (COLD-PCR) is a new form of PCR that selectively amplifies mutation-conta