924 Long-Term Outcome Following Infliximab Therapy in Pediatric Patients with Crohn Disease: Results from a Multicenter Study
β Scribed by Jeffrey S. Hyams; Trudy Lerer; Marian D. Pfefferkorn; Subra Kugathasan; Jonathan Evans; Anthony R. Otley; Anne M. Griffiths; Ryan S. Carvalho; David R. Mack; Athos Bousvaros; Joel R. Rosh; Petar Mamula; M. Susan Moyer; Marsha H. Kay; Wallace Crandall; Maria Oliva-Hemker; David Keljo; Neal S. LeLeiko; James Markowitz
- Book ID
- 119428498
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 218 KB
- Volume
- 134
- Category
- Article
- ISSN
- 0016-5085
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## Background: The long-term risk of neoplasia in Crohn's disease (CD) patients treated with infliximab is undefined. The aim was to assess, in a multicenter, matched-pair study, whether infliximab use in CD is associated with an increased frequency of neoplasia in the long term. Methods: A multic
Background: We examined short-and long-term benefits and safety of infliximab (IFX) in a population-based cohort of Crohn's disease (CD) patients <17 years old at diagnosis. ## Methods: The following parameters were assessed: short-and long-term efficacy of IFX, impact of drug efficacy, and mode