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9208 POSTER Activity of CKD-581, Histone Deacetylase Inhibitor, in Cutaneous T-cell Lymphoma Models

โœ Scribed by Kim, M.J.; Lee, C.S.; Lee, D.H.; Yang, H.M.; Lim, I.T.; Bae, D.I.; Choe, Y.J.; Kim, D.H.; Kim, S.K.; Lee, S.S.


Book ID
122450858
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
42 KB
Volume
47
Category
Article
ISSN
0959-8049

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Activity of deacetylase inhibitor panobi
โœ Wenlin Shao; Joseph D. Growney; Yun Feng; Gregory O'Connor; Minying Pu; Wenjing ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 567 KB

## Abstract Panobinostat (LBH589) is a highly potent deacetylase inhibitor that has demonstrated clinical efficacy in patients with advanced cutaneous Tโ€cell lymphoma (CTCL). To gain a better understanding of the compound activity in this tumor type, we investigated the cellular and molecular effec