92 Molecular interactions of polysialic acid, a carbohydrate involved in cell adhesion and bacterial meningitis

The polysialic acid modification of the

The polysialic acid modification of the neural cell adhesion molecule is involved in spatial learning and hippocampal long-term potentiation

✍ C.G. Becker; A. Artola; R. Gerardy-Schahn; T. Becker; H. Welzl; M. Schachner 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 959 KB

The a-2,Slinked polysialic acid (PSA) modification of the neural cell adhesion molecule (NCAM) modulates morphogenetic cell interactions. PSA is strongly expressed during neural development and generally down-regulated in the adult. However, it remains prominent in some areas of the brain, e.g., the