905 A RETROSPECTIVE STUDY OF ENTECAVIR THERAPY IN CHRONIC SEVERE HEPATITIS B
β Scribed by J. Chen
- Book ID
- 117377910
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 50 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0168-8278
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Entecavir is a potent nucleoside inhibitor of the hepatitis B virus (HBV) polymerase with a high antiviral efficacy and a high genetic barrier to viral resistance. After approval in 2006, knowledge on the side effect profile in patients with advanced liver disease and impaired liver function is stil
This study was undertaken to compare the early antiviral activity and viral kinetic profiles of entecavir (ETV) versus adefovir (ADV) in hepatitis B e antigen positive nucleoside-naΓ―ve adults with chronic hepatitis B (CHB). Sixty-nine nucleoside-naΓ―ve CHB patients with baseline HBV DNA of 10(8) copi