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9-β-D-Arabinofuranosyl-2-fluoroadenine 5′-monophosphate pharmacokinetics in plasma and tumor cells of patients with relapsed leukemia and lymphoma

✍ Scribed by Lynn Danhauser; William Plunkett; Michael Keating; Fernando Cabanillas


Book ID
104689706
Publisher
Springer
Year
1986
Tongue
English
Weight
756 KB
Volume
18
Category
Article
ISSN
0344-5704

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## BACKGROUND. T-cell lymphoid blastic phase (BP) transformation is rare in chronic myelogenous leukemia (CML). 2-amino-9-␤-D-arabinosyl-6-methoxy-9H-guanine (GW506U78), a prodrug of arabinosylguanine (ara-G), is effective in T-cell leukemias. ## METHODS. The authors present a case of a 48-year