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9-cis-retinoid acid inhibits TLR ligand- and cytokine-induced TSLP production in human keratinocytes

✍ Scribed by Xie, Yang; Takai, Toshiro; Chen, Xue; Okumura, Ko; Vicheth, Chan; Ikeda, Shigaku; Ogawa, Hideoki

Book ID: 121949990
Publisher: Elsevier Science
Year: 2013
Tongue: English
Weight: 69 KB
Volume: 69
Category: Article
ISSN: 0923-1811
DOI: 10.1016/j.jdermsci.2012.11.551

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## Abstract Abstract vitamin D receptor (VDR) and retinoid X receptor (RXR) heterodimerize to mediate the genomic actions of 1α,25‐dihydroxyvitamin D~3~ (1α,25(OH)~2~D~3~, calcitriol), the biologically active form of vitamin D~3~. In this study, we show that 9‐__cis__ retinoic acid (9‐cisRA), the l