HLA class I allelic diversity and progre
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Keyur Patel; Suzanne Norris; Lauralynn Lebeck; Anne Feng; Michael Clare; Stephen
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Article
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2006
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John Wiley and Sons
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English
⚖ 153 KB
👁 2 views
Patients infected with HIV-1 who are heterozygous at HLA class I loci present greater variety of antigenic peptides to CD8+ cytotoxic T lymphocytes, slowing progression to AIDS. A similar broad immune response in chronic hepatitis C (CHC) infection could result in greater hepatic injury. Although sp