𝔖 Bobbio Scriptorium
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8703376 Monoclonal antibody and process for its preparation


Book ID
122681093
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
60 KB
Volume
5
Category
Article
ISSN
0734-9750

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Preparation of chlorin e6–monoclonal ant
✍ Shun-ichiro Ogura; Yutaka Fujita; Toshiaki Kamachi; Ichiro Okura πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 77 KB

Chlorin e6 ( Ce 6) was conjugated with anti-tumor monoclonal antibody ( IgG 2 b ) to increase its binding affinity for tumors. The Ce 6 was activated by N -hydroxysuccinimide and directly conjugated with IgG 2 b ( IgG 2 b – Ce 6) via peptide bonds. An average of 11 Ce 6 molecules were coupled to eac