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86. Functional and histopathological age-related changes of the ear in the MPS IIIB mouse

✍ Scribed by Patricia Schachern; Vladimir Tsuprun; Sebahattin Cureoglu; Michael Paparella; Steven Juhn; Chester Whitley


Book ID
116988271
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
43 KB
Volume
93
Category
Article
ISSN
1096-7192

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## Abstract Peptidylarginine deiminases (PADs) are a group of posttranslational modification enzymes that citrullinate (deiminate) protein arginine residues in a Ca^2+^‐dependent manner. Enzymatic citrullination abolishes positive charges of native protein molecules, inevitably causing significant