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850a The treatment-naive microbiome in early-onset Crohn's Disease

✍ Scribed by Gevers, Dirk; Kugathasan, Subra; Denson, Lee; Vázquez-Baeza, Yoshiki; Van Treuren, Will; Ren, Boyu; Schwager, Emma; Knights, Dan; Song, Se Jin; Yassour, Moran; Morgan, Xochitl; Kostic, Aleksandar D.; Luo, Chengwei; Gonzalez, Antonio; McDonald, Daniel; Haberman, Yael; Walters, Thomas D.; Baker, Susan S.; Rosh, Joel R.; Stephens, Michael C.; Heyman, Melvin B.; Markowitz, James; Baldassano, Robert; Griffiths, Anne M.; Sylvester, Francisco A.; Mack, David R.; Kim, Sandra; Crandall, Wallace; Hyams, Jeffrey S.; Huttenhower, Curtis; Knight, Rob; Xavier, Ramnik J.


Book ID
122311099
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
143 KB
Volume
146
Category
Article
ISSN
0016-5085

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Background: We examined short-and long-term benefits and safety of infliximab (IFX) in a population-based cohort of Crohn's disease (CD) patients <17 years old at diagnosis. ## Methods: The following parameters were assessed: short-and long-term efficacy of IFX, impact of drug efficacy, and mode