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85: CCR7 expression by recipient T-cells and dendritic cells attenuates the development of transplant arteriosclerosis

✍ Scribed by S.M. Ensminger; S.N. Helm; L. Ohl; M. Wollin; T. Fischlein; M. Weyand; R. Forster


Book ID
116518998
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
66 KB
Volume
25
Category
Article
ISSN
1557-3117

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✍ Kristin Hochweller; Stephen M. Anderton πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 443 KB πŸ‘ 1 views

## Abstract Steady‐state dendritic cells (DC) present peptide‐MHC complexes to T cells in a tolerogenic manner, presumably because of deficient costimulation. However, it is clear that the path to tolerance involves initial T cell activation, suggesting that the deficit may lie in late‐acting costi