843 Immunoglobulin G4 Plasma Cell Bias in de novo Autoimmune Hepatitis Patients
β Scribed by Castillo-Rama, Marcela; Sasatomi, Eizaburo; Sebagh, Mylene; Randhawa, Parmjeet; Isse, Kumiko; Humar, Abhinav; Demetris, Anthony J.
- Book ID
- 122139816
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 95 KB
- Volume
- 142
- Category
- Article
- ISSN
- 0016-5085
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De novo autoimmune hepatitis has been described in both pediatric and adult liver transplantation (LT) recipients. Studies of small numbers of patients have proposed it to be an alloimmune hepatitis or form of chronic rejection. We have recently noted an increasing number of patients with post-LT re
## CD4ΨCD25Ψ regulatory T cells (T-regs ) are central to the maintenance of immune tolerance and represent an immune intervention candidate in autoimmune hepatitis (AIH), a condition characterized by impaired T-reg number and function. We investigated whether T-regs can be expanded from the existi