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836 IMPAIRED LIVER REGENERATION IN MICE LACKING GLYCINE-N-METHYLTRANSFERASE

✍ Scribed by M. Varela-Rey; N. Beraza; D. Fernandez; N. Martinez-Lopez; N. Embade; L. Gomez; M. Vazquez Chantada; J. Rodriguez; Z. Luka; C. Wagner; S.C. Lu; M.L. Martinez Chantar; J.M. Mato

Book ID
117377841
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
46 KB
Volume
50
Category
Article
ISSN
0168-8278

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πŸ“œ SIMILAR VOLUMES

Impaired liver regeneration in mice lack
Impaired liver regeneration in mice lacking glycine N-methyltransferase
✍ Marta Varela-Rey; David FernΓ‘ndez-Ramos; Nuria MartΓ­nez-LΓ³pez; Nieves Embade; La πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 558 KB

Hepatic S-adenosylmethionine (SAMe) is maintained constant by the action of methionine adenosyltransferase I/III (MATI/III), which converts methionine into SAMe and glycine N-methyltransferase (GNMT), which eliminates excess SAMe to avoid aberrant methylation reactions. During liver regeneration aft