820 Development of a Quantitative RON SRM Assay for Use in Formalin Fixed Tumor Tissues

A simple and sensitive assay for the qua

A simple and sensitive assay for the quantitative analysis of paclitaxel in human and mouse plasma and brain tumor tissue using coupled liquid chromatography and tandem mass spectrometry

✍ E. Stokvis; M. Ouwehand; L. G. A. H. Nan; E. M. Kemper; O. van Tellingen; H. Ros 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 146 KB 👁 1 views

## Abstract The development and validation of an assay for the determination of paclitaxel in human plasma, human brain tumor tissue, mouse plasma and mouse brain tumor tissue is described. Paclitaxel was extracted from the matrices using liquid–liquid extraction with __tert__‐butyl methyl ether, f