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819 Can inhibition of epidermal growth factor receptor (EGFR) with gefitinib (‘iressa’, ZD1839) improve response to ionising radiation in bladder cancer cell lines?

✍ Scribed by A.J. Colquhoun; S.P. Wozniak; E.M. Tulchinsky; M. Kriajevska; J.K. Mellon


Book ID
118646020
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
214 KB
Volume
3
Category
Article
ISSN
1569-9056

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ZD1839 (Iressa), a novel epidermal growt
✍ Neil G. Anderson; Tawhid Ahmad; Kai Chan; Richard Dobson; Nigel J. Bundred 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 French ⚖ 192 KB 👁 1 views

Overexpression of the growth factor receptors EGFR and erbB2 occurs frequently in several human cancers and is associated with aggressive tumour behaviour and poor patient prognosis. We have investigated the effects of ZD1839 (Iressa), a novel EGFR tyrosine kinase inhibitor, on the growth, in vitro