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807-2 Selective inhibition of human cardiac Kir2.2 inward rectifier channels by adrenergic alpha-1a receptors

✍ Scribed by Edgar Zitron; Claudia Kiesecker; Sonja Lück; Eberhard Scholz; Dierk Thomas; Sven Kathöfer; Volker A.W Kreye; Wolfgang Schoels; Hugo A Katus; Christoph A Karle


Book ID
119548320
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
92 KB
Volume
43
Category
Article
ISSN
1558-3597

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Kir2.2 inward rectifier potassium channe
✍ Anthony Collins; Maureen K. Larson 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 137 KB

## Abstract We previously showed inhibition of K~ir~2 inward rectifier K^+^ channels expressed in __Xenopus__ oocytes by the mitochondrial agents carbonyl cyanide p‐trifluoromethoxyphenylhydrazone (FCCP) and sodium azide. Mutagenesis studies suggested that FCCP may act via phosphatidylinositol 4,5‐