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8018 CTNNB1 promoter methylation in ovarian carcinomas is associated with loss of beta catenin expression and poor patient survival

✍ Scribed by Rodrigues, C.; Macedo-Pinto, I.; Pereira, D.; Dias, P.; Costa, V.; Rodrigues, A.; Ebert, M.


Book ID
123345459
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
45 KB
Volume
7
Category
Article
ISSN
1359-6349

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## Abstract ## BACKGROUND: Abnormal activation of the Wnt/β‐catenin signaling pathway is common and critical in the pathogenesis of digestive cancers. In this study, the authors investigated the promoter methylation of the dickkopf homolog 3 gene __Dkk‐3__ in these cancers and its prognostic signi