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8012 Combined effects of cyclooxygenase-1 and cyclooxygenase-2 selective inhibitors on the growth of ovarian carcinoma in vivo

✍ Scribed by Li, W.; Ji, Z.L.; Wang, J.; Jiang, H.R.

Book ID
121922420
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
47 KB
Volume
7
Category
Article
ISSN
1359-6349

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Combined effects of cyclooxygenase-1 and
Combined effects of cyclooxygenase-1 and cyclooxygenase-2 selective inhibitors on intestinal tumorigenesis in adenomatous polyposis coli gene knockout mice
✍ Tomohiro Kitamura; Masaki Itoh; Tetsuo Noda; Mamoru Matsuura; Keiji Wakabayashi πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 French βš– 88 KB

## Abstract As with cyclooxygenase (COX)‐2, genetic disruption of __COX‐1__ gene or pharmacologic inhibition of its activity has been shown to decrease the number of intestinal polyps in __Apc__ gene‐deficient mice. The present study was designed to investigate the combined effects of COX‐1 and COX