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8-Prenylnaringenin, the phytoestrogen in hops and beer, upregulates the function of the E-cadherin/catenin complex in human mammary carcinoma cells

✍ Scribed by Haojing Rong; Tom Boterberg; Julie Maubach; Christophe Stove; Herman Depypere; Séverine Van Slambrouck; Rudolphe Serreyn; Denis De Keukeleire; Marc Mareel; Marc Bracke


Book ID
114493182
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
186 KB
Volume
80
Category
Article
ISSN
0171-9335

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E-cadherin is the major cell-cell adhesion molecule expressed by epithelial cells. Cadherins form a complex with three cytoplasmic proteins, ␣-, ␤-, and ␥-catenin, and the interaction between them is crucial for anchoring the actin cytoskeleton to the intercellular adherens junctions. The invasive b