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8-Oxoguanine in a quadruplex of the human telomere DNA sequence

✍ Scribed by Michaela Vorlícková; Martin Tomasko; Andras J. Sagi; Klara Bednarova; Janos Sagi

Book ID
111314154
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
281 KB
Volume
279
Category
Article
ISSN
1432-1327

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## Abstract Human telomeric DNA consists of tandem repeats of the sequence 5′‐d(TTAGGG)‐3′. Guanine‐rich DNA, such as that seen at telomeres, forms G‐quadruplex secondary structures. Alternative forms of G‐quadruplex structures can have differential effects on activities involved in telomere mainte