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8 ORAL Endothelin-1 stimulates colorectal cancer adjacent fibroblasts

โœ Scribed by J. Knowles; M. Loizidou; M. Dashwood; D. Abraham; S. Xu; I. Taylor


Book ID
117568605
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
62 KB
Volume
32
Category
Article
ISSN
0748-7983

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Endothelin-1 stimulates colon cancer adj
โœ Jonathan P. Knowles; Xu Shi-Wen; Samer-ul Haque; Ashish Bhalla; Michael R. Dashw ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 840 KB

Endothelin-1 (ET-1) is produced by and stimulates colorectal cancer cells. Fibroblasts produce tumour stroma required for cancer development. We investigated whether ET-1 stimulated processes involved in tumour stroma production by colonic fibroblasts. Primary human fibroblasts, isolated from normal