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8-OH-DPAT, a 5-HT1A agonist and ritanserin, a 5-HT2A/C antagonist, reverse haloperidol-induced catalepsy in rats independently of striatal dopamine release

✍ Scribed by Guillaume Lucas; Norbert Bonhomme; Philippe De Deurwaerdère; Michel Le Moal; U. Spampinato


Publisher
Springer
Year
1997
Tongue
English
Weight
404 KB
Volume
131
Category
Article
ISSN
0033-3158

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5-HT1a agonist ±- 8-OH-DPAT modulates ba
✍ Ann M. Rasmusson; Lee E. Goldstein; Ariel Y. Deutch; Benjamin S. Bunney; Robert 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 851 KB

Serotonergic 5-HTIa agonists have recently been suggested to be effective in the treatment of human anxiety disorders. The neural mechanisms responsible for their clinical efficacy are unknown. In this study we investigated the effects of k 8 - hydroxy-2(di-n-propylamino)tetralin [ & 8-OH-DPAT], a s