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8-Nitroxanthine, a product of myeloperoxidase, peroxynitrite, and activated human neutrophils, enhances generation of superoxide by xanthine oxidase

✍ Scribed by George C Yeh; Jeffrey P Henderson; Jaeman Byun; D André d’Avignon; Jay W Heinecke


Book ID
117042587
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
236 KB
Volume
418
Category
Article
ISSN
0003-9861

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## Objective: To investigate the role of intercellular adhesion molecule 1 (icam-1) and beta2 integrins in the production of superoxide (o2-) by c1q-stimulated human polymorphonuclear leukocytes (pmn). ## Methods: Pmn were pretreated with f(ab')2 fragments of monoclonal antibodies (mab) that bloc