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8-Hydroxyquinoline inhibits iNOS expression and nitric oxide production by down-regulating LPS-induced activity of NF-κB and C/EBPβ in Raw 264.7 cells

✍ Scribed by Young-Ho Kim; Kyung Jin Woo; Jun Hee Lim; Shin Kim; Tae Jin Lee; Eun Mi Jung; Jin-Man Lee; Jong-Wook Park; Taeg Kyu Kwon

Book ID: 116290018
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 499 KB
Volume: 329
Category: Article
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2005.01.159

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## Abstract Dioscorealide B (DB), a naphthofuranoxepin has been purified from an ethanolic extract of the rhizome of __Dioscorea membranacea__ Pierre ex Prain & Burkill which has been used to treat inflammation and cancer in Thai Traditional Medicine. Previously, DB has been reported to have anti‐i