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8-Hydroxy-2′-deoxyguanosine formation during the catalytic oxidation of hydrazines in the presence of 2′-deoxyguanosine

✍ Scribed by Peter M. Gannett; Naresh S. Dalal; Xianglin Shi; Bela Toth


Book ID
113137402
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
926 KB
Volume
80
Category
Article
ISSN
0009-2797

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Formation of 8-hydroxy-2′-deoxyguanosine
✍ Keisei Okamoto; Shinya Toyokuni; Koji Uchida; Osamu Ogawa; Jun Takenewa; Ynshiyu 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 French ⚖ 559 KB

To study the possible involvement of reactive oxygen species (ROS) in the tumor biology of human renal-cell carcinoma (RCC), we analyzed 35 cases of RCC for 2 parameters of oxidative damage: 8-hydroxy-2'-deoxyguanosine (8-OHdG), a mutation-prone DNA-base-modified product, was measured by means of hi