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8-Hydroxy-2′-deoxy-guanosine is a risk factor for development of hepatocellular carcinoma in patients with chronic hepatitis C virus infection

✍ Scribed by Makoto Chuma; Shuhei Hige; Mitsuru Nakanishi; Koji Ogawa; Mitsuteru Natsuizaka; Yoichi Yamamoto; Masahiro Asaka


Book ID
108951924
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
223 KB
Volume
23
Category
Article
ISSN
0815-9319

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## Abstract ## BACKGROUND Hepatic steatosis is one of the histopathologic features of chronic hepatitis C. It was reported recently that the expression of hepatitis C virus (HCV) core protein in transgenic mice induced hepatocellular carcinoma (HCC) in association with steatosis. The objective of